To evaluate the role of renal duplex ultrasonography in the detection of early alte-ration of renal blood flow in type I diabetic patients, we studied with duplex ultrasound 32 patients with type I diabetes mellitus (19 males, 13 females, age range 8-19 years) and 35 age and sex-matched controls.The resistivity indices (RIs) and pulsatility indices royal nomadic 5413 rug (PIs) of the main renal as well as intra-renal arteries were calculated.Compared with the healthy control subjects, diabetic patients had significantly higher resistivity indices (RIs) in the intrarenal (segmental, arcuate and interlobar) ar-teries (P= 0.001).
The study, also revealed a significantly positive correlation between the RIs in the intrarenal arteries in diabetics and the albumin/creatinine ratio (r= 0.54, 0.52 and 0.51 respectively), glycated hemoglobin (r= 0.
61, 0.59 and 0.63 abc material respectively), as well as the estimated GFR (e-GFR) (r= 0.53, 0.
51 and 0.57 respectively).We conclude that the current study documented early intra-renal hemodynamic alterations in the form of pathologically elevated intrarenal RIs.This denotes the potential usefulness of duplex evaluation of the intrarenal arteries, as a noninvasive procedure, for monitoring type 1 diabetic patients to predict those at risk of diabetic nephropathy.